MineralocorticoidFludrocortisone mineralocorticoid wikipedia, sold under the brand name Florinef among others, is a corticosteroid mineralocorticoid wikipedia is used to treat adrenogenital syndromepostural hypotensionand adrenal insufficiency. Common side effects include high blood pressureswelling, heart failureand low blood potassium. Fludrocortisone was patented in tren quito Fludrocortisone has been used in the treatment of cerebral salt wasting syndrome. Fludrocortisone is also a confirmation test for diagnosing Mineralocorticoid wikipedia syndrome aldosterone producing-adrenal wikipefiathe fludrocortisone suppression test.
Mineralocorticoid - Simple English Wikipedia, the free encyclopedia
Fludrocortisone , sold under the brand name Florinef among others, is a corticosteroid which is used to treat adrenogenital syndrome , postural hypotension , and adrenal insufficiency. Common side effects include high blood pressure , swelling, heart failure , and low blood potassium. Fludrocortisone was patented in Fludrocortisone has been used in the treatment of cerebral salt wasting syndrome.
Fludrocortisone is also a confirmation test for diagnosing Conn's syndrome aldosterone producing-adrenal adenoma , the fludrocortisone suppression test. Loading the patient with fludrocortisone would suppress serum aldosterone level in a normal patient, whereas the level would remain elevated in a Conn's patient.
The fludrocortisone suppression test is an alternative to the NaCl challenge which would use normal saline or NaCl tablets. Fludrocortisone is a corticosteroid and acts as a powerful mineralocorticoid along with some additional but comparatively very weak glucocorticoid activity. Renin plasma, sodium, and potassium is checked through blood tests in order to verify that the correct dosage is reached. The acetate form of fludrocortisone, fludrocortisone acetate, is the C21 acetate ester of fludrocortisone,   and is hydrolyzed into fludrocortisone in the body.
Fludrocortisone was described in the literature in  and was introduced for medical use as the acetate ester in Fludrocortisone is marketed mainly under the brand names Astonin and Astonin-H, whereas the more widely used fludrocortisone acetate is sold mainly as Florinef but also under several other brand names including Cortineff, Florinefe, and Fludrocortison.
Fludrocortisone is marketed in Austria , Croatia , Denmark , Germany , Luxembourg , Romania , and Spain , whereas fludrocortisone acetate is more widely available throughout the world and is marketed in the United States , Canada , the United Kingdom , various other European countries, Australia , Japan , China , Brazil , and many other countries.
From Wikipedia, the free encyclopedia. Elks 14 November The Dictionary of Drugs: Chemical Data, Structures and Bibliographies. Archived from the original on 5 November Archived from the original on Archived from the original on 5 July Retrieved 8 December Archived from the original on 24 December Retrieved 24 December Archived PDF from the original on 13 December BNF 69 69 ed.
Centers for Medicare and Medicaid Services. Foye's Principles of Medicinal Chemistry. Br J Clin Pharmacol. Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Glucocorticoids and antiglucocorticoids H Cortisone Cortisone acetate Cortodoxone cortexolone, deoxycortisol Desoxycortone deoxycortone, cortexone, deoxycorticosterone Desoxycortone esters Hydrocortisone cortisol Hydrocortisone esters Prebediolone acetate Pregnenolone Pregnenolone acetate Pregnenolone succinate.
Cortisol-like and related unsubstituted: Chloroprednisone Cloprednol Difluprednate Fludrocortisone Flugestone acetate flurogestone acetate Fluocinolone Fluorometholone Fluorometholone acetate Fluperolone Fluperolone acetate Fluprednisolone Fluprednisolone esters Loteprednol Medrysone Methylprednisolone Methylprednisolone esters Prednicarbate Prednisolone Prednisone Tixocortol Tixocortol pivalate Methasones and related substituted: Amcinonide Budesonide Ciclesonide Deflazacort Desonide Fluclorolone acetonide flucloronide Fludroxycortide flurandrenolone, flurandrenolide Flunisolide Fluocinolone acetonide Fluocinonide Formocortal fluoroformylone Halcinonide Triamcinolone acetonide Triamcinolone acetonide esters.
Aglepristone Ketoconazole Mifepristone Ulipristal acetate. Mineralocorticoids and antimineralocorticoids H Desoxycortone desoxycorticosterone Desoxycortone esters Hydrocortisone cortisol Hydrocortisone esters Fludrocortisone Fludrocortisone acetate Methylprednisolone Methylprednisolone esters Prednisolone Prednisolone esters Prednisone Prednisone esters.
Natural Cortisone Cortisone acetate Cortodoxone cortexolone, deoxycortisol Desoxycortone deoxycortone, cortexone, deoxycorticosterone Desoxycortone esters Hydrocortisone cortisol Hydrocortisone esters Prebediolone acetate Pregnenolone Pregnenolone acetate Pregnenolone succinate.
Agonists Cortisol-like and related unsubstituted: