hypogonadismLow testosterone definition of Low testosterone by Medical dictionary https: Gonads are the organs of sexual differentiation—in the female, they are ovaries; in anadrol side effects heart male, the testes. Along with producing eggs and sperm, they produce sex testosteorne that generate all the differences between men and women. If they produce too little sex hormone, then either the growth of the sexual organs or their medical terminology for low testosterone is impaired. The gonads are not independent in their function, however.
Low testosterone | definition of Low testosterone by Medical dictionary
Low testosterone definition of Low testosterone by Medical dictionary https: Gonads are the organs of sexual differentiation—in the female, they are ovaries; in the male, the testes. Along with producing eggs and sperm, they produce sex hormones that generate all the differences between men and women. If they produce too little sex hormone, then either the growth of the sexual organs or their function is impaired. The gonads are not independent in their function, however. They are closely controlled by the pituitary gland.
The pituitary hormones are the same for males and females, but the gonadal hormones are different. Men produce mostly androgens, and women produce mostly estrogens. These two hormones regulate the development of the embryo, determining whether it is a male or a female.
They also direct the adolescent maturation of sex organs into their adult form. Further, they sustain those organs and their function throughout the reproductive years. The effects of estrogen reach beyond that to sustain bone strength and protect the cardiovascular system from degenerative disease.
Hormones can be inadequate during or after each stage of development—embryonic and adolescent. During each stage, inadequate hormone stimulation will prevent normal development. After each stage, a decrease in hormone stimulation will result in failed function and perhaps some shrinkage. The organs affected principally by sex hormones are the male and female genitals, both internal and external, and the female breasts.
Body hair, fat deposition, bone and muscle growth, and some brain functions are also influenced. Sex is determined at the moment of conception by sex chromosomes. Females have two X chromosomes, while males have one X and one Y chromosome.
If the male sperm with the Y chromosome fertilizes an egg, the baby will be male. This is true throughout the animal kingdom. Genetic defects sometimes result in changes in the chromosomes. If sex chromosomes are involved, there is a change in the development of sexual characteristics. Female is the default sex of the embryo, so most of the sex organ deficits at birth occur in boys. Some, but not all, are due to inadequate androgen stimulation. The penis may be small, the testicles undescended cryptorchidism or various degrees of "feminization" of the genitals may be present.
After birth, sexual development does not occur until puberty. Hypogonadism most often shows up as an abnormality in boys during puberty. Again, not every defect is due to inadequate hormones.
Some are due to too much of the wrong ones. Kallmann's syndrome is a birth defect in the brain that prevents release of hormones and appears as failure of male puberty. Some boys have adequate amounts of androgen in their system but fail to respond to them, a condition known as androgen resistance. Female problems in puberty are not caused by too little estrogen. Even female reproductive problems are rarely related to a simple lack of hormones, but rather to complex cycling rhythms gone wrong.
All the problems with too little hormone happen during menopause , which is a normal hypogonadism. A number of adverse events can damage the gonads and result in decreased hormone levels. The childhood disease mumps , if acquired after puberty, can infect and destroy the testicles—a disease called viral orchitis. Ionizing radiation and chemotherapy , trauma, several drugs spironolactone, a diuretic and ketoconazole, an antifungal agent , alcohol, marijuana , heroin, methadone , and environmental toxins can all damage testicles and decrease their hormone production.
Severe diseases in the liver or kidneys, certain infections, sickle cell anemia, and some cancers also affect gonads.
To treat some male cancers, it is necessary to remove the testicles, thereby preventing the androgens from stimulating cancer growth. This procedure, still called castration or orchiectomy , removes androgen stimulation from the whole body. For several reasons the pituitary can fail.
It happens rarely after pregnancy. It used to be removed to treat advanced breast or prostate cancer. Sometimes the pituitary develops a tumor that destroys it. Failure of the pituitary is called hypopituitarism and, of course, leaves the gonads with no stimulation to produce hormones. Biopsy — Surgical removal of pieces of tissue for examination. Embryo — Refers to life before birth, specifically the first two months after conception. Fetus — The unborn person or animal, still in the womb.
Hypothalamus — Part of the brain just above the pituitary that stimulates pituitary gland function. Ionizing radiation — X rays.
Diagnostic x rays are too weak to do damage under normal circumstances, but x rays used to treat cancer must be used with great care. Undescended testicle — A testicle that is still in the groin and has not made its way into the scrotum. Besides the tissue changes generated by hormone stimulation, the only other symptoms relate to sexual desire and function.
Libido is enhanced by testosterone, and male sexual performance requires androgens. The role of female hormones in female sexual activity is less clear, although hormones strengthen tissues and promote healthy secretions, facilitating sexual activity.
Presently, there are accurate blood tests for most of the hormones in the body, including those from the pituitary and even some from the hypothalamus. Chromosomes can be analyzed, and gonads can, but rarely are, biopsied. Replacement of missing body chemicals is much easier than suppressing excesses. Estrogen replacement is recommended for nearly all women after menopause for its many beneficial effects.
Estrogen can be taken by mouth, injection, or skin patch. It is strongly recommended that the other female hormone, progesterone, be taken as well, because it prevents overgrowth of uterine lining and uterine cancer.
Testosterone replacement is available for males who are deficient. Called also hypergonadotropic eunuchoidism. Called also hypogonadotropic eunuchoidism. Inadequate gonadal function, as manifested by deficiencies in gametogenesis or the secretion of gonadal hormones; results in atrophy or deficient development of secondary sexual characteristics and, when occurring in prepubertal males, in altered body habitus, characterized by a short trunk and long limbs.
Inadequate functioning of the testes or ovaries as manifested by deficiencies in gametogenesis or the secretion of gonadal hormones. The condition may be primary or caused by a gonadal dysfunction involving the Leydig's cells in the male, or it may be secondary to a hypothalamus or pituitary disorder.
Secondary hypogonadism is sometimes further differentiated into pituitary hypogonadism and hypothalamic hypogonadism. Cf Androgen replacement therapy. Inadequate gonadal function, as manifested by deficiencies in gametogenesis or the secretion of gonadal hormones. Inadequate gonadal function, as manifested by deficiencies in gametogenesis or secretion of gonadal hormones.
Manifestations include eunuchism, eunuchoidism, Frohlich's syndrome, amenorrhea, and incomplete development or maintenance of secondary sex characteristics. References in periodicals archive? Reduced sexual interest or drive is the symptom most strongly linked to low testosterone , along with a decrease in muscle strength and a loss of vitality and general well-being.
Low testosterone in aging men is well known to contribute to the loss of lean body mass muscle tissue and correspondent increase in body fat; at the same time, the anabolic hormone testosterone exerts positive effects on bone density as well.
More work is needed to define a cutpoint for low testosterone that, with good sensitivity and specificity, identifies men who are more likely to die early. Low testosterone and risk of premature death in older men: Low testosterone affects 4 to 5 million men over the age of 39 and is associated with a multitude of symptoms including loss of libido and sexual function, decreased energy, increased body fat, osteoporosis, reduced muscle mass, and loss of body hair.
Doctors typically treat men for hypogonadism if they have symptoms of low testosterone and their testosterone levels are below nanograms per deciliter. Middle-aged men taking testosterone to treat 'low T' triple in last decade. So, low testosterone results in obesity and diabetes, and, by itself, obesity and diabetes can decrease testosterone," explained Dr El Hashimi.
Diabetic men have another option. Adult men with a varicocele and low testosterone also should consider microsurgery sooner rather than later, indicates Goldstein. Lower levels linked to testicular varicoceles. Testosterone replacement slashes mortality: If low testosterone is the problem then Viagra won't be the answer on its own. The actual intent of the research funded by the National Institutes of Health and the American Diabetes Association was to refine testing methods for low testosterone levels.
In fact, the survey showed that more than one-third admitted to experiencing symptoms associated with low testosterone levels-- depression, erectile dysfunction, and fatigue. What men need to know: The link between low testosterone and erection problems is less clear as some men with low levels have normal erections while others do not.
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