Saizen 8mg — What does HGH do?The originating document has been archived. We cannot confirm the completeness, accuracy and currency of the content. Every effort has been made somatrolin ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information somatropin saizen 8 mg been compiled for use by healthcare practitioners and consumers in the United States.
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NE Local product name: What Saizen is and what it is used for 2. Before you use Saizen 3. How to use Saizen 4. Possible side effects 5. Merck Serono Bari Technical layout ref: This therapy is given to adults who have a serious growth hormone de ciency that has been medically diagnosed by a test.
The doctor or pharmacist will be able to explain why this medicine has been given to you or to your child. Saizen is a growth hormone. Saizen s main action is to increase growth in children and adolescents and to treat adults with growth hormone de ciency.
The growth hormone somatropin contained in Saizen is almost the same as human s natural growth hormone except that it is made outside the body by a process called recombinant DNA technology genetic engineering. Code B In children and adolescents: Take special care with Saizen Saizen therapy should be carried out under regular guidance of a doctor who is experienced in the diagnosis and management of patients with growth hormone de ciency.
Shortly after Saizen is given, you or your child may feel shaky or light-headed due to low blood sugar levels. These feelings will quickly disappear. Some children with growth hormone de ciency have developed leukaemia increased number of white blood cells , whether or not they have received treatment with growth hormone. However there is no evidence that leukaemia incidence is increased in growth hormone recipients without predisposing factors. No cause and effect relationship with growth hormone treatment has been proven.
Hip problems may occur more commonly in children with hormone or kidney problems. If your child has chronic renal failure, which can occur when kidneys are damaged, he or she should be examined periodically for evidence of bone disease.
It is uncertain whether the bone disease in children with hormone or kidney problems is affected by growth hormone therapy. X-rays of the hip should be obtained prior to initiating therapy. If your child develops a limp or complains of hip or knee pain while being treated with Saizen, tell your doctor. Treatment with Saizen will be stopped in children with chronic kidney failure at the time of kidney transplant.
Saizen is not indicated for the long-term treatment of paediatric patients who have growth failure due to genetically confirmed Prader-Willi Syndrome, unless they also have a diagnosis of growth hormone de ciency. There have been reports of sleep apnoea and sudden death after initiating therapy with growth hormone in paediatric patients with PraderWilli Syndrome who had one or more of the following risk factors: Growth hormone should generally not be used by people who are seriously ill.
If you do not respond to the therapy with Saizen, you may have developed antibodies to growth hormone. Your doctor will conduct appropriate tests to determine this. If you are over 60 years old or if you are taking Saizen for a long time you should be examined more frequently by your doctor. As there is less experience both in the treatment of older people and in prolonged treatment with Saizen, special care is required.
Using other medicines It is usually safe to use other medicines. However, if you or your child are using corticosteroids, it is important to tell the doctor or pharmacist. These medicines could interact with Saizen and therefore your doctor may need to adjust the dose of these medicines or your Saizen dose.
Corticosteroids are used to treat several illnesses including asthma, allergies, kidney rejection and rheumatoid arthritis. Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Pregnancy and breast feeding Ask your doctor or pharmacist for advice before taking any medicine. There is currently insuf cient evidence from human studies on the safety of growth hormone treatment during pregnancy and breast feeding.
Saizen should be discontinued, if pregnancy occurs. If you become pregnant tell your doctor immediately. Consult your doctor before taking Saizen if you are breast feeding.
Driving and using machines No studies on the effects of Saizen on the ability to drive and use machines have been performed. Somatropin-containing products have no influence on the ability to drive and use machines.
You should check with your doctor or pharmacist if you are not sure. Dosage It is recommended that Saizen be administered at bedtime. The dose and frequency of administration of Saizen will be decided by your doctor and will depend on your or your child s body weight or body surface area. If your daughter is treated for Turner Syndrome and she receives non-androgenic anabolic steroids as well , growth response may be enhanced.
Ask your doctor or pharmacist if you are not sure about these drugs. At the start, low doses of 0. The dose will be adjusted in stages by your doctor. The recommended nal dose of growth hormone rarely exceeds 1.
In general the lowest ef cacious dose that works for you should be administered. If you are older or overweight, a lower dose may be necessary. Method and route of administration The dose and frequency of administration of Saizen will be decided by your doctor and will depend on your or your child s size or body weight. In general Saizen 8 mg click. The produc t powder in vials must be reconstituted with the enclosed bacteriostatic solvent using the click.
The reconstituted solution is intended for subcutaneous administration under the skin and should be clear with no particles. If the solution contains particles, it must not be injected. The reconstituted solution contains 8 mg of Saizen 5. Important information Patients should be thoroughly instructed in the reconstitution procedure. For young children, the reconstitution process should be supervised by an adult. For administration of Saizen 8 mg click.
When the medicine is injected into the same place every time for a long time, it can cause damage. It is important to keep changing the place where you have your injection. Your doctor or pharmacist can speak to you about which part of the body you should use. You may need to read it again. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. Do not use Saizen and tell your doctor - If you or your child are allergic hypersensitive to somatropin or any of the other ingredients of Saizen or the liquid used to make up the injection.
Tumours must be inactive and you must have nished your anti-tumour treatment before you start your treatment with Saizen. Treatment with Saizen has to be stopped in children with chronic kidney disease at time of kidney transplantation. Your or your child s blood sugar levels may then rise above normal hours after administration. Since treatment with growth hormone can alter how your body handles sugar, your or your child s sugar levels will be tested regularly by a doctor.
Somatropin may cause you or your child s blood sugar to increase. If you or your child are diabetic or a member of your family has diabetes, your doctor will monitor closely your blood sugar level and may adjust the treatment for diabetes while you are being treated with Saizen.
Please be aware that you may need regular eye tests after having this medicine. Saizen may affect how your thyroid works. Your doctor may test your blood for levels of thyroid hormones and prescribe another hormone if you or your child are found to have developed a lack of thyroid hormone. Saizen may cause uid retention in adult patients. This may appear as swelling and joint or muscle pain. If you feel these symptoms tell your doctor who may decide to adjust your dose of Saizen.
If in the past you or your child have had a condition affecting the brain, e. Please note that there is no evidence to suggest that the use of Saizen increases the chances of such conditions coming back. Some patients may develop swelling of the brain, while taking Saizen. In this case it may be necessary to stop the growth hormone treatment, although treatment may be re-started at a later date.
If the symptoms of brain swelling come back, treatment with Saizen should be discontinued.